A Crack In Creation

Author: Jennifer Doudna
Publisher: Vintage
ISBN: 9781784702762
File Size: 25,26 MB
Format: PDF
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A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all. It is an invention that allows us to rewrite the genetic code that shapes and controls all living beings with astonishing accuracy and ease. Thanks to it, the dreams of genetic manipulation have become a stark reality: the power to cure disease and alleviate suffering, to create new sources of food and energy, as well as to re-design any species, including humans, for our own ends. Jennifer Doudna is the co-inventor of this technology - known as CRISPR - and a scientist of worldwide renown. Writing with fellow researcher Samuel Sternberg, here she provides the definitive account of her discovery, explaining how this wondrous invention works and what it is capable of. She also asks us to consider what our new-found power means: how do we enjoy its unprecedented benefits while avoiding its equally unprecedented dangers? The future of humankind - and of all life on Earth - is at stake. This book is an essential guide to the path that now lies ahead.

A Crack In Creation

Author: Jennifer A. Doudna
Publisher: Houghton Mifflin Harcourt
ISBN: 0544716965
File Size: 68,18 MB
Format: PDF
Read: 1830
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A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery, and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?

Summary Study Guide A Crack In Creation

Author: Lee Tang
Publisher: LMT Press via PublishDrive
ISBN: 0995943168
File Size: 57,69 MB
Format: PDF, Docs
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The Power and Peril of Gene Editing CRISPR/Cas9 Technology The must-read summary of “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution” by Jennifer A. Doudna and Samuel H. Sternberg. This complete summary of Jennifer Doudna and Samuel Sternberg’s book tells the story of CRISPR and “gene-editing.” CRISPR is a cutting-edge gene-editing technology that mimics what happens naturally in bacteria. It enables scientists to “play god” with plant or animal DNA, with unlimited power and peril. The technology of gene editing is the most important advance in our era. The possibility of forever altering the genetic composition of humankind is frightening. Yet we can’t overlook the opportunities that may lead to inventions for cures of HIV, debilitating genetic diseases, and cancers, and end food shortages. The book will demystify this exciting area of science and inspire you to seek answers to tough moral and ethical questions on the use of this technology. This guide includes: Book Summary—The summary helps you understand the key ideas and recommendations. OnlineVideos—On-demand replay of public lectures, and seminars on the topics covered in the chapter. Value-added of this guide: Save time Understand key concepts Expand your knowledge Read this summary and get involved in the debate on the moral and ethical issues on the use of this technology.

Life S Greatest Secret

Author: Matthew Cobb
Publisher: Basic Books
ISBN: 0465062660
File Size: 71,20 MB
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Everyone has heard of the story of DNA as the story of Watson and Crick and Rosalind Franklin, but knowing the structure of DNA was only a part of a greater struggle to understand life’s secrets. Life’s Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had farreaching consequences for how we understand ourselves and our place in the natural world, and for how we might take control of our (and life’s) future. Life’s Greatest Secret mixes remarkable insights, theoretical dead-ends, and ingenious experiments with the swift pace of a thriller. From New York to Paris, Cambridge, Massachusetts, to Cambridge, England, and London to Moscow, the greatest discovery of twentieth-century biology was truly a global feat. Biologist and historian of science Matthew Cobb gives the full and rich account of the cooperation and competition between the eccentric characters—mathematicians, physicists, information theorists, and biologists—who contributed to this revolutionary new science. And, while every new discovery was a leap forward for science, Cobb shows how every new answer inevitably led to new questions that were at least as difficult to answer: just ask anyone who had hoped that the successful completion of the Human Genome Project was going to truly yield the book of life, or that a better understanding of epigenetics or “junk DNA” was going to be the final piece of the puzzle. But the setbacks and unexpected discoveries are what make the science exciting, and it is Matthew Cobb’s telling that makes them worth reading. This is a riveting story of humans exploring what it is that makes us human and how the world works, and it is essential reading for anyone who’d like to explore those questions for themselves.

The Crack In The Cosmic Egg

Author: Joseph Chilton Pearce
Publisher: Simon and Schuster
ISBN: 1594778663
File Size: 45,35 MB
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The classic work that shaped the thought of a generation with its powerful insights into the true nature of mind and reality. • Defines culture as a "cosmic egg" structured by the mind's drive for logical ordering of its universe. • Provides techniques allowing individuals to break through the vicious circle of logic-based systems to attain expanded ways of creative living and learning. The sum total of our notions of what the world is--and what we perceive its full potential to be--form a shell of rational thought in which we reside. This logical universe creates a vicious circle of reasoning that robs our minds of power and prevents us from reaching our true potential. To step beyond that circle requires a centering and focus that today's society assaults on every level. Through the insights of Teilhard, Tillich, Jung, Jesus, Carlos Castaneda, and others, Joseph Chilton Pearce provides a mode of thinking through which imagination can escape the mundane shell of current construct reality and leap into a new phase of human evolution. This enormously popular New Age classic is finally available again to challenge the assumptions of a new generation of readers and help them develop their potential through new creative modes of thinking. With a masterful synthesis of recent discoveries in physics, biology, and psychology, Pearce reveals the extraordinary relationship of mind and reality and nature's blueprint for a self-transcending humanity.

The Crack In The Lens

Author: Darlene A. Cypser
Publisher: Foolscap & Quill LLC
ISBN: 0971855269
File Size: 53,25 MB
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If someone had asked Sherlock Holmes later in the year, there is little doubt that he would have said his life began that spring day in 1871 when he met Violet Rushdale upon the moors and ended in the winter some months distant. His mother would have disputed the former claim, and many, both friend and foe, would come to deny the latter. Yet what happened that year nearly cost him his life and his sanity, and strongly influenced the man he was to become.It is well known that the toughest steel that makes the sharpest swords must be plunged into the fire, then beaten and reshaped. So it is as well with the best and wisest of men.

Life At The Speed Of Light

Author: J. Craig Venter
Publisher: Penguin
ISBN: 0143125907
File Size: 56,52 MB
Format: PDF, Mobi
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The author of A Life Decoded explains how his team's achievement with sequencing the human genome has launched an important age of biological research, revealing a growing potential for enabling humans to adapt and evolve for long-term survival and environmental improvement.

Modern Prometheus

Author: Jim Kozubek
Publisher: Cambridge University Press
ISBN: 1108454623
File Size: 56,74 MB
Format: PDF
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This book tells the dramatic story of Crispr and the potential impact of this gene-editing technology.

Almost Human

Author: Lee R. Berger
Publisher: National Geographic Books
ISBN: 1426218117
File Size: 10,10 MB
Format: PDF, ePub, Mobi
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"In 2013, Lee Berger ... caught wind of a cache of bones in a hard-to-reach underground cave in South Africa. He put out a call around the world for petite collaborators--men and women small and adventurous enough to be able to squeeze through 8-inch tunnels to reach a sunless cave 40 feet underground. With this team of 'underground astronauts,' Berger made the discovery of a lifetime: hundreds of prehistoric bones, including entire skeletons of at least 15 individuals, all perhaps two million years old. Their features combined those of known prehominids like Lucy, the famous Australopithecus, with those more human than anything ever before seen in prehistoric remains"

The Book Of Lost Things

Author: John Connolly
Publisher: Simon and Schuster
ISBN: 0743298853
File Size: 76,38 MB
Format: PDF, Kindle
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Taking refuge in fairy tales after the loss of his mother, twelve-year-old David finds himself violently propelled into an imaginary land in which the boundaries of fantasy and reality are disturbingly melded. By the author of The Black Angel. 75,000 first printing.